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About our Research
The Heaslip lab is focused on understanding the biology of human pathogen Toxoplasma gondii, an obligate intracellular protozoan parasite and the causative agent of Toxoplasmosis.
T. gondii is transmitted to humans through consumption of raw or undercooked meat or ingestion of oocysts from soil or litter boxes in which infected cats have defecated.
Approximately 1 in 5 people worldwide are chronically infected with the parasite. Although infections in immune competent individuals are often asymptomatic, T. gondii causes life-threatening disease in immunocompromised persons. Additionally, if acute infection occurs during pregnancy, the parasite can be transmitted to the fetus causing blindness, brain damage or death.
MCB Micro Journal Club4:00pm
Monday, October 26th, 2020
04:00 PM - 05:00 PM
Storrs Campus onlineDan Phillips will lead us in a discussion of:
Kent AG, Vill AC, Shi Q, Satlin MJ, Brito IL. Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C. Nat Commun. 2020 Sep 1;11(1):4379. doi: 10.1038/s41467-020-18164-7. PMID: 32873785; PMCID: PMC7463002.
If you'd like to join the discussion:
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- Oct 29 MCB PSM Professional Development Seminar5:00pm
MCB Research Seminar: Grady and Haarer12:20pm
Friday, October 30th, 2020
12:20 PM - 01:00 PM
Other OnlineMCB Research Seminar
Patrick Grady, R. O'Neill Lab
“Do wallabies drive? Examining hypotheses of centromere and CENP co-evolution in macropods”
Elena Haarer, Campellone Lab
“Linking the Actin Cytoskeleton to Genomic Integrity and Cell Senescence”
Seminar Link: https://us.bbcollab.com/collab/ui/session/guest/0453116de50844fe86f3edee5f7c6cc4
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- Nov 2 WINS: Fixed Vs. Growth Mindset12:00pm
MCB Seminar Series: Dr. Wendy Mok3:30pm
Tuesday, November 3rd, 2020
03:30 PM - 04:30 PM
Other OnlineMCB Seminar Series:
Wendy Mok, Assistant Professor, Dept. of Molecular Biology & Biophysics, UCONN Health
Host: Victoria Robinson
"Bacteria in Sickness: How Persisters Recover from Antibiotic Treatment"
Summary: Depending on their metabolic state, bacteria may not necessarily die during antibiotic treatment. In this talk, I will discuss our work on investigating the environmental signals and molecular events that influence bacterial death and persistence following antimicrobial therapy.
Dr. Mok completed her Ph.D. with Dr. Yingfu Li at McMaster University in Hamilton, Ontario. Her doctoral thesis focused on bacterial toxin-antitoxin systems. This work sparked her interest in bacterial stress response and persistence, and this led her to complete her postdoctoral training in Dr. Mark Brynildsen’s lab in the Department of Chemical and Biological Engineering at Princeton University. At Princeton,she investigated the metabolic responses of bacterial persisters that enable them to overcome antibiotic treatment and contribute to infection relapse. In 2019,she joined MBB at UCONN Health, where research in her lab focuses on environmental triggers that impact persister formation and survival.
To learn more about Dr. Mok and her work, visit
and her website at:
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